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The Great American Smokeout is held the third Thursday in November each year to encourage smokers to quit their habit.

Sponsored by the American Cancer Society, the Smokeout is a 24-hour marathon of non-puffing. According to studies those who go 20 minutes without smoking see a decrease in their heartrate and blood pressure. After 12 hours, the body begins to cleanse the carbon monoxide from the last cigarette ingested. After one day, the risk of heart attack decreases along with heart disease and stroke.

Those holding out for two days experience a more profound sense of taste and smell. By day three, nicotine is leaving the body and withdrawal may occur. Symptoms may include nicotine cravings, anxiety, irritability, depression and weight gain.

To observe, of course, don’t smoke for the 24-hour period.

The first Great American Smokeout was held Nov. 16, 1977, in San Francisco’s Union Square.

To learn about the evils of smoking, watch Superman take on the villain responsible for the death of over 400,000 people each year. According to the Center for Disease Control, more than 16 million Americans are living with a disease caused by smoking. For every smoker-related death, 30 people live with a serious smoking-related illness.

Approximately seven-million people die from smoking each year worldwide.